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Tocris Bioscience™ W 54011
High affinity C5a receptor antagonist
$412.96 - $1699.40
Specifications
| Chemical Name or Material | N-[[4-(Dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamide hydrochloride |
|---|---|
| CAS | 405098-33-1 |
| Target | Complement Signaling inhibitors |
| Molecular Formula | C30H36N2O2.HCl |
| Formula Weight | 493.08 |
Description
High affinity C5a receptor antagonist (Ki = 2.2 nM). Inhibits C5a-induced generation of reactive superoxide species, chemotaxis and intracellular Ca2+ mobilization in human neutrophils (IC50 values are 1.6, 2.7 and 3.1 nM, respectively).Specifications
| N-[[4-(Dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamide hydrochloride | |
| Complement Signaling inhibitors | |
| 493.08 |
| 405098-33-1 | |
| C30H36N2O2.HCl | |
| >98% |
Safety and Handling
Recommended Storage : Store at -20°C
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