QoL, CIs, QALYs, and Individualized Rehabilitation: The Clinical and Practical Benefits of Regularly Assessing the Quality of Life of Adult Cochlear Implant Recipients
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Assessments and Intervals
2.2.1. Generic QoL
2.2.2. Disease-Specific QoL
2.3. Bias
2.4. Statistics
3. Results
3.1. Participants
3.2. Generic QoL
3.3. Disease-Specific QoL
3.3.1. SSQ12
3.3.2. NCIQ
3.4. Audio Processor Daily Use
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Appendix A
SSD | AHL | Unilateral | |
---|---|---|---|
Cochlear implant | |||
SONATATI | 8 | 10 | 15 |
SYNCHRONY | 7 | 7 | 6 |
SYNCHRONY PIN | 0 | 5 | 15 |
CONCERTO | 1 | 2 | 9 |
CONCERTO PIN | 1 | 1 | 2 |
Missing | 0 | 1 | 11 |
Total | 17 | 26 | 58 |
Audio processor | |||
SONNET | 12 | 17 | 39 |
RONDO | 4 | 2 | 8 |
OPUS 2 | 0 | 3 | 5 |
Missing | 1 | 4 | 6 |
Total | 17 | 26 | 58 |
Electrode array | |||
FLEX28 | 8 | 13 | 30 |
FLEX24 | 4 | 6 | 9 |
FLEX20 | 1 | 2 | 1 |
FLEXSOFT | 0 | 1 | 0 |
MEDIUM | 0 | 1 | 0 |
COMPRESSED | 0 | 1 | 3 |
STANDARD | 4 | 1 | 4 |
Missing | 0 | 1 | 11 |
Total | 17 | 26 | 58 |
n | Visit 1 | n | Visit 2 | n | Visit 3 | |
---|---|---|---|---|---|---|
SSD | 16 | 0.61 (0.54–0.89) | 15 | 0.83 (0.74–0.88) | 14 | 0.85 (0.77–0.96) |
AHL | 22 | 0.48 (0.35–0.67) | 20 | 0.68 (0.55–0.79) | 19 | 0.74 (0.65–0.81) |
Unilateral | 45 | 0.45 (0.36–0.56) | 43 | 0.67 (0.55–0.79) | 40 | 0.69 (0.50–0.74) |
Visit | n | Total | Wilcoxon Signed-Rank Test (p-Values 2-Sided) | ||
---|---|---|---|---|---|
V1 vs. V2 | V1 vs. V3 | ||||
SSD | 1 | 17 | 5.1 (4.2–6.4) | 0.034 | 0.020 * |
2 | 16 | 6.1 (4.8–6.8) | |||
3 | 16 | 6.6 (5.8–7.0) | |||
AHL | 1 | 25 | 2.8 (1.2–2.5) | <0.001 * | <0.001 * |
2 | 24 | 4.5 (3.3–6.5) | |||
3 | 23 | 5.2 (4.0–6.5) | |||
Unilateral | 1 | 42 | 2.3 (1.2–2.5) | <0.001 * | <0.001 * |
2 | 42 | 4.4 (2.8–5.6) | |||
3 | 38 | 4.8 (3.4–6.1) |
Visit 1 | Visit 2 | Visit 3 | Wilcoxon Signed-Rank Test (p-Values 2-Sided) | ||||||
---|---|---|---|---|---|---|---|---|---|
n | Median (IQR) | n | Median (IQR) | n | Median (IQR) | V1 vs. V2 | V1 vs. V3 | ||
SSD | Basic sound perception | 14 | 68.8 (60.6–82.5) | 11 | 80.0 (63.8–83.8) | 12 | 86.3 (68.8–90.6) | 0.046 | 0.016 * |
Advanced sound perception | 11 | 92.5 (70.0–97.5) | 10 | 95.0 (80.0–97.5) | 9 | 97.5 (82.5–97.5) | 0.159 | 0.237 | |
Advanced speech production | 10 | 76.3 (54.4–90.0) | 10 | 85.0 (70.0–93.1) | 7 | 80.0 (67.5–91.3) | 0.028 | 0.237 | |
Self-esteem | 10 | 65.0 (58.8–74.4) | 9 | 72.5 (70.0–82.5) | 9 | 75.0 (72.5–82.5) | 0.107 | 0.051 | |
Activity limitations | 15 | 82.5 (71.3–86.3) | 14 | 87.5 (80.6–95.0) | 14 | 93.8 (85.6–97.5) | 0.074 | 0.003 * | |
Social interactions | 6 | 68.8 (58.8–76.9) | 6 | 75.0 (69.4–82.5) | 5 | 75.0 (72.5–77.5) | 0.042 | 0.068 | |
AHL | Basic sound perception | 18 | 56.3 (35.6–66.9) | 18 | 65.0 (48.1–75.0) | 17 | 72.5 (67.5–77.5) | 0.005 * | 0.001 * |
Advanced sound perception | 19 | 72.5 (55.0–83.8) | 17 | 82.5 (67.5–87.5) | 18 | 78.8 (75.0–86.9) | 0.006 * | 0.001 * | |
Advanced speech production | 21 | 52.5 (35.0–75.0) | 19 | 70.0 (52.5–80.0) | 19 | 72.5 (62.5–85.0) | 0.014 * | 0.001 * | |
Self-esteem | 19 | 60.0 (50.0–68.8) | 14 | 70.0 (64.4–74.4) | 17 | 72.5 (65.0–75.0) | 0.016 * | 0.010 * | |
Activity limitations | 12 | 62.5 (45.6–75.6) | 12 | 75.0 (69.4–80.6) | 10 | 77.5 (71.9–79.4) | 0.009 * | 0.033 | |
Social interactions | 8 | 46.3 (27.5–60.0) | 6 | 70.0 (63.8–72.5) | 8 | 65.0 (58.1–69.4) | 0.068 | 0.043 | |
Unilateral | Basic sound perception | 42 | 35.0 (20.0–49.4) | 39 | 62.5 (48.8–81.3) | 36 | 71.3 (59.4–80.6) | <0.001 * | <0.001 * |
Advanced sound perception | 35 | 70.0 (52.5–78.8) | 36 | 82.5 (68.8–92.5) | 30 | 83.8 (67.5–95.0) | 0.008 * | <0.001 * | |
Advanced speech production | 40 | 32.5 (15.0–48.1) | 35 | 50.0 (38.8–61.3) | 34 | 57.5 (48.1–64.4) | <0.001 * | <0.001 * | |
Self-esteem | 41 | 42.5 (30.0–52.5) | 35 | 65.0 (45.0–73.8) | 35 | 62.5 (55.0–77.5) | <0.001 * | <0.001 * | |
Activity limitations | 29 | 40.0 (30.0–70.0) | 27 | 77.5 (55.0–86.3) | 25 | 77.5 (75.0–85.0) | <0.001 * | 0.001 * | |
Social interactions | 20 | 47.5 (27.5–55.6) | 14 | 65.0 (52.5–73.1) | 17 | 67.5 (60.0–77.5) | 0.013 * | 0.002 * |
Hours per Day | |||||||
---|---|---|---|---|---|---|---|
n | 3–5 | 6–8 | 9–12 | 12–15 | >15 | ||
AHL | Visit 2 | 19 | 0% | 0% | 36.8% | 52.6% | 10.6% |
Visit 3 | 24 | 0% | 0% | 41.7% | 50.0% | 8.3% | |
SSD | Visit 2 | 16 | 0% | 0% | 12.5% | 62.5% | 25.0% |
Visit 3 | 16 | 6.3% | 6.3% | 25.0% | 50.0% | 12.5% | |
Unilateral | Visit 2 | 49 | 0% | 6.1% | 32.7% | 44.9% | 16.3% |
Visit 3 | 42 | 0% | 2.4% | 28.6% | 57.1% | 11.9% |
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n | Age at Time of Testing (Years) | n | Age at Implantation (Years) | n | Duration of Deafness in Implanted Ear (Years) | |
---|---|---|---|---|---|---|
SSD | 17 | 39.5 (16.4–66.4) | 16 | 39.9 (16.8–66.1) | 15 | 25.3 (9–67) |
AHL | 26 | 64.6 (28.3–79.6) | 22 | 64.6 (29.0–78.4) | 17 | 18.8 (2–48) |
Unilateral | 58 | 58.7 (24.1–84.7) | 52 | 60.3 (26.2–85.8) | 41 | 20.2 (2–63) |
SSD | AHL | Unilateral | ||||
---|---|---|---|---|---|---|
Intervals | 1 v 2 | 1 v 3 | 1 v 2 | 1 v 3 | 1 v 2 | 1 v 3 |
HUI-3 | Yes | Yes | Yes | Yes | Yes | Yes |
SSQ12 (total score) | No | Yes | Yes | Yes | Yes | Yes |
NCIQ | ||||||
Basic sound perception | No | Yes | Yes | Yes | Yes | Yes |
Advanced sound perception | No | No | Yes | Yes | Yes | Yes |
Advanced speech production | No | No | Yes | Yes | Yes | Yes |
Self-esteem | No | No | Yes | Yes | Yes | Yes |
Activity limitations | No | Yes | Yes | No | Yes | Yes |
Social interactions | No | No | No | No | Yes | Yes |
Total | 5/16 | 13/16 | 16/16 |
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Lassaletta, L.; Calvino, M.; Sanchez-Cuadrado, I.; Skarzynski, P.H.; Cywka, K.B.; Czajka, N.; Kutyba, J.; Tavora-Vieira, D.; Van de Heyning, P.; Mertens, G.; et al. QoL, CIs, QALYs, and Individualized Rehabilitation: The Clinical and Practical Benefits of Regularly Assessing the Quality of Life of Adult Cochlear Implant Recipients. Int. J. Environ. Res. Public Health 2023, 20, 6906. https://doi.org/10.3390/ijerph20206906
Lassaletta L, Calvino M, Sanchez-Cuadrado I, Skarzynski PH, Cywka KB, Czajka N, Kutyba J, Tavora-Vieira D, Van de Heyning P, Mertens G, et al. QoL, CIs, QALYs, and Individualized Rehabilitation: The Clinical and Practical Benefits of Regularly Assessing the Quality of Life of Adult Cochlear Implant Recipients. International Journal of Environmental Research and Public Health. 2023; 20(20):6906. https://doi.org/10.3390/ijerph20206906
Chicago/Turabian StyleLassaletta, Luis, Miryam Calvino, Isabel Sanchez-Cuadrado, Piotr Henryk Skarzynski, Katarzyna B. Cywka, Natalia Czajka, Justyna Kutyba, Dayse Tavora-Vieira, Paul Van de Heyning, Griet Mertens, and et al. 2023. "QoL, CIs, QALYs, and Individualized Rehabilitation: The Clinical and Practical Benefits of Regularly Assessing the Quality of Life of Adult Cochlear Implant Recipients" International Journal of Environmental Research and Public Health 20, no. 20: 6906. https://doi.org/10.3390/ijerph20206906